The overuse of antibiotics is common and can lead to unnecessary spending on prescription medicine, as well as increase the risk for adverse effects and antimicrobial resistance.
Yuting Zhang, Ph.D., of the University of Pittsburgh, and colleagues used Medicare data (comprising about 1 million patients per year) to examine geographic variation in antibiotic use among older adults in 306 hospital referral regions, 50 states and the District of Columbia, and four national regions (South, West, Midwest and Northeast). They also studied quarterly change in antibiotic use across the four regions.