A Taste of Good Cheer: Saffron for the treatment of cancer related depression
Jacob Schor ND
There is little about having cancer that warms the heart or that triggers glee. On a list of stressful or depressing life experiences, cancer is near the top. Thus we often find cancer patients are prescribed anti-depressant medications. In certain cancers these medications may have drawbacks.
For example it has long been a common practice to prescribe SSRI antidepressants to women taking tamoxifen as this both cheers them up and seems to reduce the drug’s side effects. There is now concern that tamoxifen’s side effects decrease because the anti-depressants by interfering with the liver’s production of a particular enzyme (cyp2d6) render tamoxifen ineffective.
These same antidepressants may reduce bone growth. Though not proven, slowing bone growth, aside from contributing to osteoporosis, may have another problem as it is generally believed that this could favor growth of cancer metastases in the bone. We would prefer bones to be growing fast and staying strong.